Research Director
National Hellenic Research Foundation
مجموع سنوات الخبرة :29 years, 7 أشهر
Important Comment: The end date given above is not correct, but the system requires end date until present and no longer. My contract will be expired at the 67th year of my age, unless resignation.
Development of the research in the field of transition metal homogeneous catalysis at the National Hellenic Research Foundation.
Further development and supervision of the research and training on the following topics:
(i) Transition metal homogeneous catalysis (with Ru, Rh, Pd, Pt):
catalysis by hybrid and hemilabile phosphorus ligands,
catalysis in air by phosphane-free ligands,
asymmetric catalysis,
catalysis by high energy techniques,
aqueous catalysis;
(ii) Catalysis by metal nanoparticles;
(iii) Dendrimer chemistry;
(iv) Bioactive compounds
Commercial product of our research:
Salicylaldehyde thiosemicarbazone palladium(II) chloride.
Reference: Kostas, I.D. et al. Tetrahedron Lett. 46 (2005) 1967.
Description: catalyst used for the Suzuki reaction under aerobic conditions.
Companies: SIGMA-ALDRICH (Product No.: 674125); SANTA CRUZ (Product No.: sc-253529); American Custom Chemicals Corporation (Product No.: CHM0157495); Catalyz Pharma Co., Ltd. (Product No.: 8790); ENERGY CHEMICAL (Product No.: 674125); Shanghai Hanhong Chemical Co., Ltd. (Product No.: RA10460092); Chengdu Ai Keda Chemical Technology Co., Ltd. (Product No.: 104729); ABI (Product No.: AC2A01FOP); ChemDBPortal (Product No.: CDBP225501); ALPHA CHEMISTRY; Haihang Industry Co., Ltd.; Jinan Haohua Industry Co., Ltd.; Angene International Ltd.; Jinan Great Chemical Industry Co., Ltd.; Huiju Chem Co., Ltd.; Tractus Company Ltd.; and more …
Highlights of our research activities:
(a) First use of metalloporphyrins as catalysts in the Suzuki reaction and the hydrogenation of trans-cinnamaldehyde - recyclable catalysts in aqueous media (Tetrahedron Lett. 2007, 48, 6688; Eur. J. Inorg. Chem. 2011, 4709).
(b) Me-ANILAPHOS: a highly versatile chiral ligand for the Rh-catalyzed asymmetric olefin hydrogenation (Tetrahedron Lett. 2006, 47, 7947). K.A. Vallianatou was awarded by the “Leonidas Zervas” Prize in Organic Chemistry (5/3/2008) for her PhD Thesis in “Asymmetric Catalysis” supervised by I.D. Kostas.
(c) Pioneers on the use of thiosemicarbazones as ligands in the Pd-catalyzed coupling reactions in air (Tetrahedron Lett. 2004, 45, 2923; Tetrahedron Lett. 2005, 46, 1967; Tetrahedron Lett. 2006, 47, 4403).
(d) First use of a hemilabile amino- and sulfur-containing phosphinite as efficient ligand in the Pd-catalyzed Heck reaction (Tetrahedron 2003, 59, 3467).
(e) First use of non cyclic-amino bisphosphinites as efficient ligands in the Rh-catalyzed hydroformylation (J. Organomet. Chem. 2001, 626, 221).
Writing of proposals submitted for funding. Coordinator and/or participant in National and European competitive funded projects. Incoming funds to the Centre attributed to I.D. Kostas' initiative as principal investigator or co-investigator for the period 2005-2012: 916, 982 Euros.
Writing of scientific publications.
Member of the Internal Scientific Council of the Institute.
Teaching and supervision in training seminars.
Member of the organizing committee and/or chair in conferences, workshops, educational events.
Member of committees for MSc and PhD Theses.
Member and Rapporteur in committees for recruitment and promotion of researchers.
Establishment of National and international collaborations.
Editorial Advisory Board: “Journal of Chemistry” (2012-present), “Conference Papers in Chemistry” (2012-2015), “Dataset Papers in Chemistry” (2012-present), “ISRN Organic Chemistry” (2010-present; renamed to “International Scholarly Research Notices” in 2014), “The Open Natural Products Journal” (2009-2015), "Journal of Medicinal Chemistry & Toxicology" (2016-present).
Invited reviewer for proposals and fellowships within National, European and American programmes.
Invited reviewer for a number of papers (as well as Editor in Chief) by 44 scientific journals.
Organic synthesis of cyclodextrin derivatives.
Synthesis of new transition metal (Au, Rh) complexes with phosphanes and homogeneous catalysis.
Synthesis of new crown-ethers and their organometallic derivatives with lithium, tin, mercury, magnesium.
PhD in Organometallic Chemistry. Thesis: “Metal alkoxide modified organolithium reagents. Synthesis and stabilization of substituted lithioxyalkylithiums including the aza-analogues, in tetrahydrofuran, in the presence of magnesium 2-ethoxyethoxide” . The experimental part funded by a Doctoral Fellowship was performed at the National Hellenic Research Foundation with Dr. C.G. Screttas.
Basic Degree in General Chemistry (courses and practicals). Prize for the most excellent University students by the State Scholarships Foundation. Undergraduate Thesis in Chemistry: “1,3-Dipolar cycloaddition of nitrile oxides to 2,6-dibenzylidenecycloexanone” .